It occurred sometime between 9am and 11am on Friday 28 June 2013, from a house on Almsford Close.
The burglars stole jewellery including a diamond engagement ring, a ladies gold Rolex wristwatch and gold cufflinks.
Detective Constable Chris Spackman, of Harrogate CID, said:
If you were in the Almsford Close area around the time of the burglary, I am asking you to come forward if you noticed any unusual or suspicious activity.
I also need to speak to anyone who may have been offered any of the stolen items for sale and ask that they get in touch.
Can I remind homeowners to ensure that they lock their doors, even if they are at home. Also, if the door has a security chain, use this as well.
If you would like to know how secure your home is, why not complete the survey on our website.
For further crime prevention advice please visit www.northyorkshire.police.uk/crimeprevention.
Or call Crimestoppers anonymously on 0800 555 111 quoting reference number 12130105760.