Police are growing increasingly concerned for Wayne, whose disappearance is considered to be out of character.
Wayne was last seen around 11.30pm last night on Nesfield Close in the Middleton area of the city.
He was thought to be wearing a black hooded top with black trainers and is believed to have been using his push bike.
Wayne is described as a white male, 6ft in height with average build and brown hair.
Anyone with information is asked to contact the helpdesk at Holbeck Police Station via: 101.